The Krische Research Group

 

Graduate Students

 

Emma McInturff

elmcinturff@gmail.com

 

 

Sang Hoon Kim

shkchem@mail.utexas.edu

 

Emma was raised in Pocatello, Idaho and attended Boise State University, where she received her B.S.in 2009 in chemistry. While at Boise State, Emma studied the synthesis of aziridinomitosenes in the research laboratory of Dr. Don Warner. She also participated in a summer REU program at Syracuse University under the supervision of Dr. Nancy Totah. Emma joined the Krische group at the Unviersity of Texas in Fall of 2009.

Sang Hoon Kim was born in Seoul, South Korea in 1980 and received BS and MS degree from Sungkyunkwan University under the supervision of Prof. Chan-Mo Yu. After graduation, he joined the University of Texas at Austin for his Ph.D. education in Prof. Krische's group. He is currently doing research on crotylation.

   
 

Ryan A Mesch

ryanamesch@gmail.com

 

Xin Gao

xin.gao@mail.utexas.edu

 

Ryan is a corn-fed Ohio native who received his B.S. from Hampshire College. While studying analogue photography, he stumbled upon organic chemistry his junior year and made the decision to double major. As undergraduate, Ryan began the initial investigation into a novel Ni superoxide dismutase mimic for Lewis acid activation of carbon dioxide. Upon graduation, he skipped coasts to work at Lawrence Berkely National Laboratory in the Biological Nanostructures Facility led by Dr. Ron Zuckermann. In the Zukermann group, Ryan examined self-assembling ampiphilic sheet structures made with protein mimicking N-substituted poly-glycine chains "peptoids". In the Krische group, he plans go back to his undergraduated roots by concentrating on green chemistry methodology.

Xin was born in Nanjing, China. He attended Sichuan University in 2004, and finished his final year research project under the direction of Prof. Jingsong You in 2008. After obtained his B.S. degree in chemistry, Xin joined the University of Texas at Ausin to further his Ph.D. education in Prof. Krische's group. He is currently working on catalyzed coupling reactions of alcohol and olefins.

   
 

Joyce Leung

joyce.leung@mail.utexas.edu

 

 David del valle

  david.delvalle@mail.utexas.edu

 

Joyce was born in HK in 1985 and she moved to Califonia in 2002. She received her BS in Chemical Biology from UC Berkeley in 2007. There she performed undergraduate research involving synthesis of ligands for TRP-M8 receptors found in prostate cancer cells under the supervision of Dr. Ahamindra Jain for a year. She also worked at Nanosyn Inc. as a Research Associate in Synthetic Organic Chemistry for a year prior to Joining Krische's group. She is interested in employing the group's methodology in natural product synthesis.

1."Hydroacylation of 2-butyne from the alcohol or aldehyde oxidation level via ruthenium catalyzed C-C bond forming transfer hydrogenation." Williams, V. M.; Leung, J. C.; Patman, R. L. ; Krische, M. J. Tetrahedron, 2009, 65, 5024.

David was born in Buffalo, NY in 1980 and attended SUNY Buffalo. He earned a BS degree in Medicinal Chemistry in 2003, and continued on at Buffalo to earn a MS in Chemistry in 2005. His thesis work involved the design and synthesis of medicinally useful dyes. He was employed by AstraZeneca R&D Boston (2005-2008) working in Cancer Chemistry. Currently, he is investigating the use of recently developed asymmetric hydrogenation methods in natural products synthesis.

1."1,n-Glycols as Dialdehyde Equivalents in Iridium Catalyzed Enantioselective Carbonyl Allylation form  the Alcohol Oxidation Level and Iterative Two-Directional Assembly of 1,3-Polyols" Lu, Y. Kim, I.-S.; Hassan, A.; Del Valle, D. J.; Krische, M. J. Angew. Chem. Int. Ed. 2009, 48, 5018.

   
 

Jason Zbieg

jasonzbieg@hotmail.com

 

 Abbass Hassan

abbashassankhan@yahoo.com

 

Jason was born in New Jersey in 1984 and attended San Diego State University. He received his BS in Chemistry 2007. At SDSU he worked under the guidance of Dr. Mike Bergdahl involving the synthesis of Virginiamycin M1, synthesis of Micromide, and asymmetric 1,4 additions of monosilylzincates. He also worked twice as a summer intern in Medicinal Chemistry at Pfizer Global Research and Development-La Jolla in 2006 and 2007 under the direction of Dr. Jennifer Lafontaine and Dr. Henry Chen. There he worked on the synthesis of several novel heterocycles for the treatment of glaucoma and cancer.  In the Krische group his current project utilizes the group's catalytic hydrogenation chemistry for the asymmetric synthesis of Sertraline.

1."anti-Aminoallylation of Aldehydes via Ruthenium-Catalyzed Transfer Hydrogenative Coupling of Sulfonamido Allenes: 1,2-Aminoalcohols" Skucas, E.; Zibeg, J. R.; Krische, M.J. J. Am. Chem. Soc. 2009, 131, 5054.

Abbas was born in Mardan, Pakistan and received his MS from University of Peshawar in 2004. There he performed master's level research with Prof. M. Arfan towards the synthesis of Azaheterocyclic drugs. He than move to HEJ Research Institute of Chemistry, University of Karachi, where he worked with Prof. Khalid M. Khan  on Natural Product chemistry and towards the synthesis of Heterocyclic therapeutic agents. In Krische's group he is currently working on Hydrogen Mediated Asymmetric Aldol chemistry.

4."Elongation of 1,3-Polyols via Iterative Catalyst-Directed Carbonyl Allylation from the Alcohol Oxidation Level." Hassan, A.; Lu, Y.; Krische, M. J. Org. Lett. 2009, 11, 3112.

3."1,n-Glycols as Dialdehyde Equivalents in Iridium Catalyzed Enantioselective Carbonyl Allylation form  the Alcohol Oxidation Level and Iterative Two-Directional Assembly of 1,3-Polyols" Lu, Y. Kim, I.-S.; Hassan, A.; Del Valle, D. J.; Krische, M. J. Angew. Chem. Int. Ed. 200948, 5018.

2."Diastereo- and Enantioselective Reductive Aldol Addition of Vinyl Ketones via Catalytic Hydrogenation" Han, S. B.; Hassan, A.;  Krische, M.J. Synthesis 2008, 2669.

1."Diastereo- and Enantioselective Hydrogenative Aldol Coupling of Vinyl Ketones: Design of an Effective Monodentate TADDOL-Like Phosphonite Ligand." Bee C.; Han, S. B.; Hassan, A.; Ioda, H.; Krische, M.J. J. Am. Chem. Soc. 2008, 130, 2746.

   
 

Yu Lu

luyu@mail.utexas.edu

 

Chris Grant

chrisgra@mail.utexas.edu

 

Yu Lu was born in Jiangxi Province in China in 1983. He graduated from Fudan University with a B.S. in Chemistry. He then joined Dr. Susan Lever's group in the University of Missouri, Columbia to obtain a M.S. in Chemistry. His project there involved the synthesis of substituted diarylalkylpiperidine and diarylalkylpiperazine analogues and evaluation of them as potent receptor binding ligands. He attended the University of Texas, Austin in 2007. He is currently working on the total synthesis of bryostatin via transition-metal catalyzed reductive C-C bond formations developed in the Krische group.

3."Concise Synthesis of the Bryostatin A-Ring via Consecutive C-C Bond Forming Transfer Hydrogenations" Lu, Y.; Krische, M. J. Org. Lett. 200911, 3108.

2."Elongation of 1,3-Polyols via Iterative Catalyst-Directed Carbonyl Allylation from the Alcohol Oxidation Level." Hassan, A.; Lu, Y.; Krische, M. J. Org. Lett. 200911, 3112.

1."1,n-Glycols as Dialdehyde Equivalents in Iridium Catalyzed Enantioselective Carbonyl Allylation form  the Alcohol Oxidation Level and Iterative Two-Directional Assembly of 1,3-Polyols" Lu, Y. Kim, I.-S.; Hassan, A.; Del Valle, D. J.; Krische, M. J. Angew. Chem. Int. Ed. 200948, 5018.

Chris was born in Detroit, Michigan and received his BS in chemistry from the University of Michigan in April 2006. At U of M he performed methodological and mechanistic studies on nucleophilic asymmetric catalysis of electronically diverse benzofuranones under Dr. Edwin Vedejs. His interests include developing new methods and natural product synthesis.

2."Protecting-Group-Free Synthesis of 3-tert-Prenylated Oxindoles: Contiguous All-Carbon Quaternary Centers via Tertiary Neopentyl Substitution" Grant, C. D.; Krische, M. J. Org. Lett. 2009, 4485.

1."Branch-Selective Reductive Coupling of 2-Vinyl Pyridines and Imines via Rhodium Catalyzed C-C Bond Forming Hydrogenation." Komanduri. V.;Grant, C. D.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 12592.

   
 

 Ryan Patman

r.l.patman@mail.utexas.edu

 

 Vanessa Williams

vanessa.m.williams@mail.utexas.edu

 

Ryan was born in Elk City, Oklahoma in 1982 and attended Oklahoma State University in Stillwater. He graduated in 2006 with a BS in Chemistry and during his time there he performed research under the guidance of Dr. Richard A. Bunce involving the synthesis of dibenzo[b.f]1,4-oxazepines and their 10,11-dihydro derivatives using tandem reduction-reductive amination reactions. His current research utilizes the Krische Group's hydrogen mediated C-C bond forming reactions employing Rhodium catalysts with a focus on regio- and stereoselective control.

7."Hydroacylation of 2-butyne from the alcohol or aldehyde oxidation level via ruthenium catalyzed C-C bond forming transfer hydrogenation." Williams, V. M.; Leung, J. C.; Patman, R. L. ; Krische, M. J. Tetrahedron, 2009, 65, 5024.

6."Direct C-Vinylation of Alcohols or Aldehydes Employing Alkynes as Vinyl Donors: A Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation." Patman, R. L.; Chaulagain, M. R.; Williams, V. M.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 2066.

5."Formation of C-C Bonds via Catalytic Hydrogenation and Tranfer Hydrogenation: Vinylation, Allyation and Enolate Addition of Carbonyl Compounds and Imines." Patman, R. L.; Bower, J. F.; Kim, I. S.;  Krische, M. J. Aldrichim. Acta. 2008, 41, 95.

4."Catalytic Carbonyl Allylation and Propargylation via Transfer Hydrogenative C-C Coupling: Transcending Oxidation Level and Use of Preformed Organometallics in Carbonyl Addition" Bower, J. F.; Kim, I. S.; Patman, R. L.; Krische, M. J. Angew. Chem. Int. Ed. 2008, 48, 34.

3."Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Enynes as Surrogates to Preformed Allenylmetal Reagents: A Ruthenium Catalyzed C-C Bong Forming Transfer Hydrogenation" Patman, R. L.; Williams, V. M.; Bower, J. F.; Krische, M.J. Angew. Chem. Int. Ed. 2008, 47, 5220.

2."Iridium Catalyzed C-C Coupling via Transger Hydrogenation: Carbonyl Addition from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Cyclohexadiene." Bower, J. F.; Patman, R. L.; Krische, M.J. Org. Lett. 2008, 10, 1033.

1."Catalytic C-C Coupling via Transfer Hydrogenation: Reverse Prenylation, Crotylation and Allylation from the Alcohol or Aldehyde Oxidation Level." Bower, J.; Skucas, E.; Patman, R. L.; Krische, M.J. J. Am. Chem. Soc. 2007, 129, 15134.

Vanessa was born in southern California in 1983 and attended The University of California Riverside. She received her BS in Biochemistry with a chemistry emphasis in 2005. She worked for half a year in the Marsella group on the synthesis of cyclic enediynes(2003). Then, she worked twice as a summer intern in Medicinal Chemistry at Pfizer Global Research and Development-La Jolla in 2004 and 2005. Her current project utilizes the group's catalytic hydrogenation chemistry in the synthesis of conagenin.

4."ESI-MS, DFT and Synthetic Studies on the Hydrogen-Mediated   Coupling of Acetylene: Insertion of C=X Bonds into Rhodacyclopentadienes and Bronsted Acid Cocatalyzed Hydrogenolysis of Organorhodium Intermediates." Williams, V. M.; Kong, J.-R; Ko, B.-J.; Mantri, Y.; Brodebelt, J. S.; Baik. M.-H.; Krische, M. J. J. Am. Chem. Soc., 2009, 131, 16054.

3."Hydroacylation of 2-butyne from the alcohol or aldehyde oxidation level via ruthenium catalyzed C-C bond forming transfer hydrogenation." Williams, V. M.; Leung, J. C.; Patman, R. L.; Krische, M. J. Tetrahedron, 2009, 65, 5024.

2."Direct C-Vinylation of Alcohols or Aldehydes Employing Alkynes as Vinyl Donors: A Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation." Patman, R. L.; Chaulagain, M. R.; Williams, V. M.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 2066.

1."Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Enynes as Surrogates to Preformed Allenylmetal Reagents: A Ruthenium Catalyzed C-C Bong Forming Transfer Hydrogenation" Patman, R. L.; Williams, V. M.; Bower, J. F.; Krische, M.J. Angew. Chem. Int. Ed. 2008, 47, 5220.

   
 

Soo Bong Han

soobong75@mail.utexas.edu

 

 Ed Skucas

eskucas@mail.utexas.edu

 

Soo Bong was born in Seoul, Korea in 1975. He received a BS degreee in Chemistry from Sogang University (2002) and his MS degree from KAIST (2004) under the supervision of Prof. Sukbok Chang. After woking as a senior researcher at LG Life Sciences, he began doctoral studies under the supervision of Prof. Michael J. Krische at the University of Texas at Austin. He is currently working on Iridium catalyzed C-C bond formation under transfer hydrogenation condition.

8."Iridium Catalyzed Carbonyl Allylation form the Alcohol Oxidation Level via Transfer Hydrogenation: Minimum Pre-Activation, Maximum Synthetic Efficiency."  Han, S. B.; Kim, I. S.; Krische, M. J. Chem. Commum. 2009, In Press.

7."Enantioselective Allyaltion, Crotylation and Reverse Prenylation of Substituted Istatins via Iridium Catalyzed C-C Bond Forming Transfer Hydrogenation." Itoh, J.; Han, S. B.; Krische, M. J. Angew. Chem. Int. Ed. 2009, 48, 6313.

6."Enantioselective Carbonyl Reverse Prenylation from the Alcohol or Aldehyde Oxidation Level Employing 1,1-Dimethylallenes as the Prenyl Donor" Han, S. B.; Kim, I. S.; Han, H; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 6916.

5."anti-Diastereo- and Enantioselective Carbonyl Crotylation from the Alcohol or Aldehyde Oxidation Level Employing a Cyclometallated Iridium Catalyst: a-Methyl Allyl Acetate as a Surrogate to Preformed Crotylmetal Reagent." Kim, I. S.; Han, S. B.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 2514.

4."Catalyst-Directed Diastereoselectivity in Hydrogenative Coupling of Acetylene to a-Chiral Aldehydes: Formal Synthesis of All Eight L-Hexoses." Han, S. B.; Kong, J.-R.; Krische, M. J. Org. Lett. 2008, 10, 4133..

3."Diastereo- and Enantioselective Reductive Aldol Addition of Vinyl Ketones via Catalytic Hydrogenation" Han, S. B.; Hassan, A.;  Krische, M.J. Synthesis 2008, 2669.

2."Diastereo- and Enantioselective Hydrogenative Aldol Coupling of Vinyl Ketones: Design of an Effective Monodentate TADDOL-Like Phosphonite Ligand." Bee C.; Han, S. B.; Hassan, A.; Ioda, H.; Krische, M.J. J. Am. Chem. Soc. 2008, 130, 2746.

1."Reductive Aldol Coupling of Divinyl Ketones via Rhodium Catalyzed Hydrogenation: syn-Diastereoselective Construction of  beta-Hydroxyenones." Han, S. B.; Krische, M. J. Org. Lett. 2006, 8, 5657.

Ed was born and raised in Vilnuis, Lithuania. He attended Vilnuis University and in 2001 moved to Philadelphia to attend Temple University. There he performed undergraduate research under Dr. F. Davis working on asymmetric synthesis of isoquinolines and later on preparation of enantiopure a-amino-ketones. Ed currently works on reductive aldol chemistry.

9."Direct Prenylation of Aromatic and alpha,beta-Unsaturated Carboxamides via Iridium-Catalyzed C-H Oxidative Addition-Allen Insertion" Zhang, Y. J.; Skucas, E.; Krische, M. J. Org. Lett. 200911, 4248.

8."anti-Aminoallylation of Aldehydes via Ruthenium-Catalyzed Transfer Hydrogenative Coupling of Sulfonamido Allenes: 1,2-Aminoalcohols" Skucas, E.; Zibeg, J. R.; Krische, M.J. J. Am. Chem. Soc. 2009, 131, 5054.

7."Ruthenium Catalyzed C-C Bond Formation via Transfer Hydrogenation : Branch-Selectie Reductive Coupling of Allens to Paraformaldehyde and Higher Aldehydes." Ngai, M.-Y.; Skucas, E.; Krische, M.J. Org. Lett. 2008, 10, 2705.

6."Catalytic C-C Coupling via Transfer Hydrogenation: Reverse Prenylation, Crotylation and Allylation from the Alcohol or Aldehyde Oxidation Level." Bower, J.; Skucas, E.; Patman, R. L.; Krische, M.J. J. Am. Chem. Soc. 2007, 129, 15134.

5."Enantiomerically Enriched Allylic Alcohols and Allylic Amines via C-C Bond Forming Hydrogenation: Asymmetric Carbonyl and Imine Vinylation," Skucas, E.; Ngai, M.-Y.; Komanduri, V.; Krische, M. J. Acc. Chem. Res. 2007, 40, 1394.

4."Carbonyl Allylation in the Absence of Preformed Allyl Metal Reagents: Reverse Prenylation via Iridium Catalyzed Hydrogenative Coupling of Dimethylallene," Skucas, E.; Bower, J.; Krische, M. J.  J. Am. Chem. Soc. 2007, 12644.

3."Enantioselective Reductive Coupling of 1,3-Enynes to Glyoxalates Mediated by Hydrogen: Asymmetric Synthesis of beta,gamma-Unsaturated a-Hydroxy Esters," Hong, Y.-T.; Cho, C.-W.; Skucas, E.; Krische, M. J. Org. Lett. 2007, 9, 3745.

2."Contrasteric Regiocontrol in Rhodium Catalyzed Hydrogenative Couplings of Nonsymmetric 1,3-Diynes to Ethyl Glyoxalate," Cho, C.-W.; Skucas, E.; Krische, M. J. Organometallics 2007, 26, 3860.

1."Enantioselective Reductive Coupling of Acetylene to N-Arylsulfonyl Imines via Rhodium Catalyzed C-C Bond Forming Hydrogenation: (Z)-Dienyl Allylic Amines." Skucas, E.; Kong, J.-R.; Krische, M.J. J. Am. Chem. Soc. 2007, 129, 7242.

   
 

   Post-Doctors

 

Dr. Angelika Preetz

apreetz@cm.utexas.edu

 

Dr. Jinhaek Yang

chemdoctor@hotmail.com

 

Angelika was born in 1980 in Stendal, Germany. She studied chemistry at the University of Rostock where she graduated in 2005. In 2002/2003 she attended the International University of Turku, Finland, as an exchange student supported by DAAD. For her diploma and Ph.D. thesis she joined the group of PD Dr. Detlef Heller. Angelika finished her Ph.D. "Rhodium precatalysts in asymmetric catalysis", which was supported by the Graduiertenkolleg 1213 (research training group 1213), in 2009. In June 2009 she joined the Krische group to work on metal-catalyzed hydrogenative coupling reactions.

Jin had earned B.S. degree from Chungnam National University and started graduate research in Korea Advanced Institute of Sciences and Technology (KAIST) under the supervision of Hee-Yoon Lee for M.S. degree. He attended the University of Wisconsin at Madison and joined  the Prof. Richard P. Hsung' group for Ph. D. Currently he is working on the natural product synthesis involving reductive coupling reactions and the development of new methods.

   
 

Dr. Hoon Han

hhsese@hanmail.net

 

Dr. Michael Rössle

mroessle@aol.com

 

Hoon was born in Korea in 1978. He received his B.S. and M.S. degree (Chemistry, and Organic Chemistry , respectively) at SungKyunKwan University (SKKU) under the supervision of Prof. Seung Soo Yoon in 2001, and 2003, respectively. During MS course, he had studied on self-assembled macromolecule chemistry and the development of new fluorescent materials for OLED (Organic Light-Emitting Device) materials. He then moved to KAIST for his Ph.D. degree and finished his Ph.D. work as Cu-catalyzed nitrogen transfer reactions under the supervision of Prof. Sukbok Chang in Feb. 2007. He focused on transition metal catalyzed C-H activation as a post-doctoral position of Brain Korea 21 (BK21) program at Natural Science Institute in KAIST for one and half year (Mar. 2007-Sep. 2008). Currently, he joined  Krische group, UT at Austin and he have focused on transition metal catalyzed asymmetric C-C coupling reactions.

2."All-Carbon Quaternary Centers via Ruthenium-Catalyzed Hydromethylation of 2-Substituted Butadienes Mediated by Formaldehyde: Beyond Hydroformylation" Smejkal, T.; Han, H; Breit, B.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 10366.

1."Enantioselective Carbonyl Reverse Prenylation from the Alcohol or Aldehyde Oxidation Level Employing 1,1-Dimethylallenes as the Prenyl Donor" Han, S. B.; Kim, I. S.; Han, H; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 6916.

Michael was born in the southern part of Germany in 1978. After attending school and community service, he started his chemistry studies at the Universität Stuttgart in 1999. Under the supervision of Prof. Dr. J. Christoffers he received his diploma degree in 2004 for the work titled: 'Ein neuer Zugang zu 1,4-Diketonen durch Cer-katalysierte Oxidationsverfahren'. Afterwards, he continued his research, then as a Ph. D. student, in the labs of Prof. Dr. J. Christoffers in Stuttgart. In February 2006 he moved along with Prof. Christoffers to the Carl von Ossietzky- Universität Oldenburg in the north of Germany, where he completed his studies in August 2008. Currently, he is working as a Feodor-Lynen-fellow of the Alexander von Humboldt foundation on the total synthesis of Hsp90 inhibitors, using novel metal catalyzed asymmetric C-C bond forming reactions.

   
 

Dr. Takeo Fukuzumi

tfukuzumi@cm.utexas.edu

 

 

 

 

Takeo was born in Nagoya, Japan in 1979 and attended Suzuki National College of Technology and then Nagoya Institute of Technology (NIT) and received his B.S. in Chemistry in 2002. He received his Ph.D. from NIT in 2007 under the supervision of Prof. Takeshi Toru and Prof. Norio Shibata. During his Ph.D. years, he focused on the enantioselective synthesis of Sulfur and Fluorine compounds. After his Ph.D., Takeo joined the Jeffrey W. Bode group at the University of Califonia at Santa Barbara (UCSB) to start his Postdoctorial research in April 2007. When Prof. Bode moved to the University of Pennsylvania (UPenn) in Oct 2007, Takeo also followed him to Upenn. He focused on Chemoselective peptide ligation reaction using Hydroxylamines and Ketoacids during his postdoc research in Bode group. In Setember 2009, Takeo joined the Krische group to work on metal-catalyzed C-C bond forming transfer hydrogenation reactions.

 

   
 

 Visiting Scholars and Students

 

Dr. Yongjian Zhang

yjian@sjtu.edu.cn

 

Alexander Haydl

Alex.Haydl@web.de

 

Yongjian was born in Jilin, China in 1973. He received his B.S. and M.S. degree in chemistry and organic chemistry at Yanbian University in 1994 and 1997, respectively. Afterwards, he worked in the same University as a lecturer, in 1999, he moved to Korea and joined the Korea Institute of Science and Technology (KIST)-Hanyang University joint degree program for his Ph. D. degree and received his Ph. D. degree in organic chemistry under the supervision of Prof. Sang-gi Lee and Prof. Jung Hoon Choi in 2003. After one year of postdoctoral research in the same lab, he returned to China, and worked at Shanghai Jiao Tong University (SJTU) starting in 2004. He was promoted to associate professor in 2005. Over the years, his research has focused on asymmetric catalysis including the development of novel chiral ligands and their applications in asymmetric reactions. In Feb. 2009, he joined the Krische group as a visiting scholar to work on the development of transition metal catalyzed C-C bond forming reactions.

1."Direct Prenylation of Aromatic and alpha,beta-Unsaturated Carboxamides via Iridium-Catalyzed C-H Oxidative Addition-Allen Insertion" Zhang, Y. J.; Skucas, E.; Krische, M. J. Org. Lett. 200911, 4248.

Alex was born in Emmendingen, in southern Germany in 1986. After attending school and absolving one year civil services, he started his chemistry studies at the Albert-Ludwigs-University in Freiburg in 2005. In 2008 he obtained his 'Vordiplom' and is now focussing on Organic Chemistry. He joined the Krische research group as an intern to get insight into new C-C coupling methods.

   
 

Alexander Henderson

ah7584@bristol.ac.uk

 

 

 

Alex was born in London, England in 1988 and is an undergraduate currently on an exchange from the University of Bristol. Having joined the Krische group for a year he is working on reductive coupling reactions.